Rapid shrinkage of a prolactin-secreting pituitary tumor with bromocriptine: CT documentation.

Prolactin-secreting pituitary tumors are now recognized as a common endocrinologic problem [1]. Bromocriptine is an ergot alkaloid which, by virtue of its agonist action at the dopamine receptor, is effective in lowering serum prolactin levels [2). Although a number of reports have shown reduction in tumor size with bromocriptine therapy [3-8], documentation of rapid regression of tumor size is limited [9]. We describe a prolactinoma patient in whom bromocriptine therapy resulted in rapid reduction in tumor size.